jimliu/science-skills

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OpenAlex Find, verify, and synthesize scientific literature — from "what's the seminal paper for X" through full multi-source …

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Borzoi (PyTorch port) Predict genome-wide functional tracks (RNA-seq, CAGE, DNase, ChIP) from DNA sequence with Borzoi. Use this skill when…

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ColabFold MSA server (api.colabfold.com) Predict protein structure for monomers and multimers with AlphaFold2 via the ColabFold runner (Mirdita et al. 2022, g…

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ColabFold MSA server (api.colabfold.com) Structure prediction for protein, nucleic-acid, and small-molecule complexes with Boltz-2 (Passaro & Wohlwend et al. …

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ColabFold MSA server (api.colabfold.com) Structure prediction for protein, nucleic-acid, and small-molecule complexes with the Chai-1 foundation model (Chai D…

jimliu/science-skills

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ColabFold MSA server (api.colabfold.com) Structure prediction using OpenFold3, an open-weights PyTorch reproduction of AlphaFold3 from the AlQuraishi Lab. Use…

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compute-env-setup Set up a compute environment on a remote provider so Claude Science jobs can run there. Covers direct SSH/conda hosts…

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customize Create, configure, and maintain custom agent profiles and author new skills via the `repl` tool. Use when the user wa…

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DiffDock-L Predict small-molecule binding poses with DiffDock-L (Corso et al. 2023/2024, github.com/gcorso/DiffDock) — blind dif…

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ESM-2 Embed proteins with Meta AI's ESM-2 (`fair-esm` package). Use this skill ML, (2) Masked-LM likelihood / mutation effe…

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ESMFold2 / ESMC Biohub ESMFold2 / ESMFold2-Fast all-atom co-folding (Candido et al. 2026, github.com/Biohub/esm). Single-sequence and…

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Evo 2 Score, embed, and generate DNA sequences with Evo 2, a long-context genomic foundation model. Use this skill when: (1…

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figure-composer Compose one publication-grade multi-panel figure. Entry from a one-line claim + data refs, OR from an existing figure…

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figure-style Publication-grade figure correctness and legibility rules. Load before drawing any plot and call `apply_figure_style(…

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indication-dossier Generate a therapeutic indication dossier. Covers the patient population, epidemiology, disease biology, standard of …

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ligandmpnn Inverse-fold a backbone with ligand, nucleic-acid, and metal context using LigandMPNN (Dauparas et al. 2023, github.c…

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managed-model-endpoints Register a model service in the managed family — a local model server container the daemon starts/stops on demand, or…

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paper-narrative Judge and reshape the STORY a paper's figures tell. Input is the work itself — manuscript (or abstract) + figure deck…

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pdf-explore Use this skill when the user has attached a PDF, paper, report, or other document and the answer needs content from m…

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product-self-knowledge Stop and consult this skill whenever your response would include specific facts about Anthropic's products. Covers: C…

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proteinmpnn Inverse-fold a protein backbone (PDB structure) into amino-acid sequence with ProteinMPNN (Dauparas et al. 2022, gith…

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remote-compute-modal Run GPU jobs on the user's own Modal account via host.compute.create('byoc:modal', ...). Covers the create→submit→wai…

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remote-compute-ssh Submit→wait_for_notification→harvest workflow for the user's SSH/SLURM hosts. Load once you've decided to dispatch re…

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scgpt Embed and annotate single-cell expression data with scGPT, a foundation model for single-cell biology. Use this skill…

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scvi-tools Probabilistic single-cell RNA-seq with scvi-tools — scVI for a batch-corrected latent space, scANVI for semi-supervis…

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self-awareness Claude Science's own session database schema and SDK surface for introspection via host.query(). Load this when you n…

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skill-creator Create new skills, modify and improve existing skills, and measure skill performance.

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solublempnn Inverse-fold a backbone with SolubleMPNN — ProteinMPNN retrained on a soluble-PDB subset (Dauparas et al. 2022) — for…

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using-model-endpoint Call a registered model endpoint over its native HTTP API from the endpoint's scoped inference kernel (BASE_URL prelo…

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