SkillsAdd

eturkes/claude-scientific-skills

ginkgo-cloud-lab

Submit and manage protocols on Ginkgo Bioworks Cloud Lab (cloud.ginkgo.bio), a web-based interface for autonomous lab execution on Reconfigurable Automation Carts (RACs). Use when the user wants to run protein expression and purification (cell-free, E. coli, or Pichia), HiBiT or A280 or LabChip quantification, IVT mRNA/circRNA synthesis, thermal shift / developability assays, Echo-MS enzyme or analyte methods, SPR target onboarding, fluorescent pixel art, or otherwise interact with Ginkgo Cloud…

First seen Apr 16, 2026

Installation

$ npx skills add eturkes/claude-scientific-skills --skill ginkgo-cloud-lab
View on skills.sh ↗ GitHub repository ↗

Summary

  • Submit and manage protocols on Ginkgo Bioworks Cloud Lab (cloud.ginkgo.bio), a web-based interface for autonomous lab execution on Reconfigurable Automation Carts (RACs).
  • Use when the user wants to run protein expression and purification (cell-free, E. coli, or Pichia), HiBiT or A280 or LabChip quantification, IVT mRNA/circRNA synthesis, thermal shift / developability assays, Echo-MS enzyme or analyte methods, SPR target onboarding, fluorescent pixel art, or otherwise interact with Ginkgo Cloud Lab services.
  • Covers protocol selection, input preparation, pricing, and ordering workflows.

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More details

Agent compatibility

Declared targets from SKILL.md / docs. Unmarked agents are not listed — the skill may still install via the CLI.

Claude Code Not declared
Cursor Not declared
Codex Not declared
GitHub Copilot Not declared
Windsurf Not declared
Gemini CLI Not declared
Cline Not declared
OpenCode Not declared

Repository health

License LICENSE.md
Default branch main
Status Active

Skill metadata

Parsed from SKILL.md frontmatter.

Version2.0
LicenseMIT license
Allowed toolsRead
More metadata
version
2.0

Package contents

Files included with this skill beyond the listing page.

  • skill md SKILL.md 7,324 B
  • docs SUMMARY.md 616 B

History

  1. First seen on skills.sh
  2. First recorded snapshot · 21 installs

SKILL.md

Ginkgo Cloud Lab

Overview

Ginkgo Cloud Lab (https://cloud.ginkgo.bio) provides remote access to Ginkgo Bioworks' autonomous lab infrastructure. Protocols are executed on Reconfigurable Automation Carts (RACs) -- modular units with robotic arms, maglev sample transport, and industrial-grade software spanning 70+ instruments.

The platform also includes EstiMate, an AI agent that accepts human-language protocol descriptions and returns feasibility assessments and pricing for custom workflows beyond the listed protocols.

The catalog is organized into Expression & Purification (in vitro / cell-free / E. coli / Pichia), Characterization & Assay, Method & Target Onboarding, and Specialty. Pick a protocol below, then read its reference file for inputs, outputs, the automated workflow, and ordering details.

Available Protocols

Expression & Purification - In vitro

Protocol Readout Price Turnaround Status
[IVT mRNA/circRNA Synthesis](references/ivt-rna-synthesis-qpcr.md) qPCR (mRNA or circRNA, 384-well) $99/sample up to 12 business days Certified

Expression & Purification - Cell-free (E. coli CFPS)

Protocol Readout Price Turnaround Status
[Validate sequence expression](references/cell-free-protein-expression-validation.md) Go/no-go titer + purity (up to 1800 bp) $39/sample up to 10 days Certified
[Optimize expression conditions](references/cell-free-protein-expression-optimization.md) DoE across 24 conditions $199/sample up to 11 days Certified
[Express + quantify (HiBiT)](references/cell-free-protein-expression-hibit.md) Luminescence, no purification $39/sample up to 11 days Certified
[Express + purify (A280)](references/cfps-strep-tag-purification-a280.md) Strep-tag, A280 yield $149/sample up to 11 days Certified
[Express + purify minibinder](references/minibinder-strep-tag-a280.md) Strep-tag, A280, LabChip $149/sample up to 11 days Certified
[Express + purify (A280 + LabChip)](references/cfps-expression-purification-quantification.md) Strep-tag, A280 + purity/size $159/sample up to 12 days Certified

Expression & Purification - E. coli

Protocol Readout Price Turnaround Status
[Express + quantify (HiBiT)](references/ecoli-protein-expression-hibit.md) Luminescence (up to 384 constructs) $79/sample up to 3 weeks Certified
[Express + purify (A280)](references/ecoli-protein-expression-histag-a280.md) His-tag, A280 yield $199/sample up to 3 weeks Certified
[Express + purify minibinder](references/ecoli-minibinder-expression-histag-a280.md) His-tag, A280 yield $199/sample up to 3 weeks Certified
[Express + purify (A280 + LabChip)](references/ecoli-expression-purification-quantification.md) His-tag, A280 + purity/size $209/sample up to 3 weeks Certified

Expression & Purification - Pichia

Protocol Readout Price Turnaround Status
[Express + quantify (LabChip)](references/pichia-protein-expression-labchip.md) Secreted protein, size/purity (up to 96) $89/sample up to 4 weeks Certified (New)

Characterization & Assay

Protocol Readout Price Turnaround Status
[Express + thermal shift](references/cfps-strep-purification-thermal-shift.md) SYPRO Orange Tm (Tonset, TM1-3) $159/sample up to 12 days Certified
[Detect enzymatic products (Echo-MS)](references/echo-ms-cfps-detection.md) Substrate/product by Echo-MS $44/sample up to 13 days Beta

Method & Target Onboarding

Protocol Readout Price Turnaround Status
[Onboard Echo-MS method](references/echo-ms-method-onboarding.md) Calibration curve, LOD/LOQ $799/molecule up to 3 weeks Certified
[Onboard SPR target](references/spr-target-onboarding.md) Validated SPR capture method $1,399/target up to 4 weeks Beta

Specialty

Protocol Readout Price Turnaround Status
[Generate fluorescent pixel art](references/fluorescent-pixel-art-generation.md) UV photo, 7-color E. coli palette $25/plate up to 7 days Beta

Coming soon: Protein Expression and Binding Affinity Characterization (express + purify, then screen binding affinity against a target).

Choosing a Protocol

  • Quick expressibility screen? Cell-free HiBiT ($39) or Validate sequence expression ($39).
  • Need purified protein + yield? A280 tiers (cell-free or E. coli); add LabChip for purity/size.
  • Difficult / membrane / disulfide / cofactor targets? Cell-free Optimize (24-condition DoE).
  • Secreted or eukaryotic targets? Pichia expression.
  • Screening de novo binders/minibinders? Cell-free or E. coli minibinder tiers, then SPR onboarding for kinetics.
  • Enzyme activity / biocatalysis? Echo-MS enzymatic detection (onboard the analyte method first).
  • Stability / developability ranking? Thermal shift assay.
  • RNA (mRNA/circRNA)? IVT synthesis + qPCR.

General Ordering Workflow

  1. Select a protocol at https://cloud.ginkgo.bio/protocols
  2. Configure parameters (number of proteins/samples/molecules/targets, replicates, plates)
  3. Download the protocol's input template and upload inputs (FASTA/CSV/XLSX for sequence protocols; Design Tool for pixel art; vendor catalog numbers for onboarding)
  4. Add any special requirements in the Additional Details field
  5. Provide an email, agree to the protocol terms, and add to cart / submit to receive a feasibility report and price quote

For protocols not listed above, use the EstiMate chat (https://cloud.ginkgo.bio/estimate) to describe a custom protocol in plain language and receive a compatibility assessment and pricing.

Authentication

Access Ginkgo Cloud Lab at https://cloud.ginkgo.bio. Account creation or institutional access may be required. Contact Ginkgo at [email protected] for access questions.

Key Infrastructure

  • RACs (Reconfigurable Automation Carts): Modular robotic units with high-precision arms and maglev transport
  • Catalyst Software: Protocol orchestration, scheduling, parameterization, and real-time monitoring
  • 70+ integrated instruments: Agilent Bravo liquid handlers, Beckman/Labcyte Echo acoustic dispensers, BMG PHERAstar / Tecan Spark readers, Revvity LabChip, Bio-Rad CFX Opus, Nicoya Alto SPR, SciEx Echo-MS, Inheco/Cytomat incubators, and more
  • Nebula: Ginkgo's autonomous lab facility in Boston, MA